Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TAS2R46 | P59540 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TAS2R31 | P59538 | 2/20 | 0.35 |
| ▸ | TAS2R10 | Q9NYW0 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220574 | 1.00 | LMNA (0.58) | LMNATSHRTAS2R46ALDH1A1NPC1 | |
| SCHEMBL937997 | 1.00 | LMNA (0.58) | LMNATSHRTAS2R46ALDH1A1NPC1 | |
| Valine SCHEMBL15477725 | 0.83 | LMNA (0.46) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL937318 | 0.82 | LMNA (0.60) | LMNATSHRTAS2R46ALDH1A1NPC1 | |
| SCHEMBL1037667 | 0.82 | LMNA (0.60) | LMNATSHRTAS2R46ALDH1A1NPC1 | |
| SCHEMBL937050 | 0.82 | LMNA (0.60) | LMNATSHRTAS2R46ALDH1A1NPC1 | |
| SCHEMBL12909964 | 0.82 | LMNA (0.66) | LMNATSHRTAS2R46ALDH1A1NPC1 | |
| SCHEMBL1783157 | 0.82 | LMNA (0.66) | LMNATSHRTAS2R46ALDH1A1NPC1 | |
| SCHEMBL15450107 | 0.82 | LMNA (0.66) | LMNATSHRTAS2R46ALDH1A1NPC1 | |
| SCHEMBL23128326 | 0.80 | LMNA (0.58) | LMNATSHRTAS2R46ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4725279-A1 | ORGANIC HETEROCYCLES FOR PHOTOELECTRIC DEVICES | Merck Patent GmbH (DE) | 2026-04-15 | — | — | EP | disclosed |
| EP-4541156-A1 | ORGANIC HETEROCYCLES FOR PHOTOELECTRIC DEVICES | Merck Patent GmbH (DE) | 2025-04-23 | — | — | EP | disclosed |
| CN-119325755-A | Organic heterocyclic compounds for optoelectronic devices | 默克专利有限公司 | 2025-01-17 | — | — | CN | disclosed |
| WO-2024256357-A1 | ORGANIC HETEROCYCLES FOR PHOTOELECTRIC DEVICES | MERCK PATENT GMBH (DE) | 2024-12-19 | — | — | WO | disclosed |
| WO-2023247338-A1 | ORGANIC HETEROCYCLES FOR PHOTOELECTRIC DEVICES | MERCK PATENT GMBH (DE) | 2023-12-28 | — | — | WO | disclosed |
| WO-2017184549-A1 | PYRROLOPYRIDINE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC (US) | 2017-10-26 | — | — | WO | disclosed |
| EP-3219713-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | Gilead Sciences, Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-2523950-B1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES INC (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9321753-B2 | Inhibitors of Flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| EP-2734515-B1 | THIOPHEN-2-CARBOXYLIC ACID DERIVATIVES USEFUL AS INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES INC (US) | 2015-11-04 | — | — | EP | disclosed |
| EP-1569929-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF i FLAVIVIRUS /i INFECTIONS | Virochem Pharma Inc. (CA) | 2005-09-07 | — | — | EP | disclosed |
| US-20050009804-A1 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS (CANADA) INCORPORATED (CA) | 2005-01-13 | — | — | US | disclosed |
| EP-1159258-B1 | AMIDE COMPOUNDS FOR THE POTENTIATION OF CHOLINERGIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20040167315-A1 | Active energy ray curable composition | KONICA MINOLTA HOLDINGS, INC. (JP) | 2004-08-26 | — | — | US | disclosed |
| WO-2004052885-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC. (CA) | 2004-06-24 | — | — | WO | disclosed |
| US-20040048904-A1 | Amide compounds for the potentiation of cholinergic activity | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
| US-6664293-B2 | For treatment and/or prevention of disorders in the central nervous system, particularly amnesia, dementia, Alzheimer's dementia | FUJIWAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| US-20030096847-A1 | Amide compounds for the potentiation of cholinergic activity | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-05-22 | — | — | US | disclosed |
| EP-1159258-A1 | AMIDE COMPOUNDS FOR THE POTENTIATION OF CHOLINERGIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000051970-A1 | AMIDE COMPOUNDS FOR THE POTENTIATION OF CHOLINERGIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009804-A1 | Compounds and methods for the treatment or prevention of Flavivirus infections | ZC3HAV1, ZYX, ZFX | LMNA 1242/4885TSHR 4286/4885TAS2R46 3695/4885 |
| US-20040048904-A1 | Amide compounds for the potentiation of cholinergic activity | CHAT, CHRM2, CHRNA2 | LMNA 2903/4885TSHR 691/4885TAS2R46 3351/4885 |
| US-20030096847-A1 | Amide compounds for the potentiation of cholinergic activity | CHAT, CHRM2, CHRNA2 | LMNA 2903/4885TSHR 691/4885TAS2R46 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.