Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037667 | 1.00 | LMNA (0.60) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL937318 | 1.00 | LMNA (0.60) | LMNATSHRALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4354664 | 0.98 | LMNA (0.58) | LMNATSHRALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL937999 | 0.98 | LMNA (0.58) | LMNATSHRALDH1A1NPC1RAB9A | |
| Ethylene SCHEMBL27605005 | 0.96 | LMNA (0.61) | LMNATSHRALDH1A1NPC1RAB9A | |
| Ethylene Glycol SCHEMBL4324703 | 0.93 | LMNA (0.53) | LMNATSHRALDH1A1NPC1RAB9A | |
| Ethylenediamine SCHEMBL3332646 | 0.91 | LMNA (0.51) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL24240093 | 0.88 | LMNA (0.47) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL10774039 | 0.88 | LMNA (0.47) | LMNATSHRALDH1A1NPC1RAB9A | |
| Propylene Glycol SCHEMBL4322377 | 0.87 | LMNA (0.47) | LMNATSHRALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111464-A1 | JAK2 V617F INHIBITORS AND METHODS OF USE THEREOF | RAYTHERA, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| WO-2021046636-A1 | CANNABINOID DERIVATIVES, PRECURSORS AND USES | KARE CHEMICAL TECHNOLOGIES INC. (CA) | 2021-03-18 | — | — | WO | disclosed |
| EP-3219713-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | Gilead Sciences, Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-3219713-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | Gilead Sciences, Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| WO-2017051355-A1 | COMPOUNDS WITH HIV MATURATION INHIBITORY ACTIVITY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-03-30 | — | — | WO | disclosed |
| EP-2523950-B1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES INC (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-2523950-B1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES INC (US) | 2017-03-15 | — | — | EP | disclosed |
| WO-2017017609-A1 | BETUIN DERIVATIVES FOR PREVENTING OR TREATING HIV INFECTIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-02-02 | — | — | WO | disclosed |
| US-9321753-B2 | Inhibitors of Flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-9321753-B2 | Inhibitors of Flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-6534434-B2 | Catalyst for unsaturated carbonyl compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-03-18 | — | — | US | disclosed |
| US-6515137-B2 | Enantioselectivity of alpha,beta-unsaturated aldehydes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-02-04 | — | — | US | disclosed |
| EP-1263735-A1 | ACID ADDITION SALTS OF IMIDAZOLIDINONES AS REACTION CATALYSTS | The Regents of The University of California (US) | 2002-12-11 | — | — | EP | disclosed |
| EP-1257519-A1 | CHEMICAL TRANSFORMATION OF SUBSTRATES USING NONMETALLIC, ORGANIC CATALYST COMPOSITIONS | The Regents of The University of California (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6369243-B1 | ACID CATALYST | THE REGENTS OF THE UNIVERISITY OF CALIFORNIA | 2002-04-09 | — | — | US | disclosed |
| US-20020016473-A1 | Catalytic processes employing chiral imidazolidinone-based catalyst composition | MACMILLAN DAVID W C (US) | 2002-02-07 | — | — | US | disclosed |
| US-20020013475-A1 | Chiral imidazolidinone-based catalyst composition and reaction system | MACMILLAN DAVID W C (US) | 2002-01-31 | — | — | US | disclosed |
| US-6307057-B1 | CATALYZE ENANTIOSELECTIVE REACTIONS, E.G., DIELS-ALDER REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-10-23 | — | — | US | disclosed |
| WO-2001053241-A1 | CHEMICAL TRANSFORMATION OF SUBSTRATES USING NONMETALLIC, ORGANIC CATALYST COMPOSITIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-07-26 | — | — | WO | disclosed |
| WO-2001053269-A1 | ACID ADDITION SALTS OF IMIDAZOLIDINONES AS REACTION CATALYSTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013475-A1 | Chiral imidazolidinone-based catalyst composition and reaction system | COASY, DHPS, INTS9 | LMNA 1342/4885TSHR 4061/4885ALDH1A1 78/4885 |
| US-20020016473-A1 | Catalytic processes employing chiral imidazolidinone-based catalyst composition | COASY, ALDH3A1, TALDO1 | LMNA 1202/4885TSHR 4574/4885ALDH1A1 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.