Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 6/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | OGT | O15294 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776792 | 0.97 | F10 (0.35) | DRD1DRD2F10SLC1A3SLC1A2 | |
| SCHEMBL28944402 | 0.97 | F10 (0.35) | DRD1DRD2F10SLC1A3SLC1A2 | |
| SCHEMBL639968 | 0.87 | USP5 (0.37) | DRD1DRD2F10SLC1A3SLC1A2 | |
| SCHEMBL639744 | 0.84 | F10 (0.37) | DRD1DRD2F10USP5OGT | |
| SCHEMBL641706 | 0.84 | F10 (0.37) | DRD1DRD2F10USP5OGT | |
| SCHEMBL27756011 | 0.83 | CYP3A4 (0.37) | F10CHRM1 | |
| SCHEMBL642721 | 0.78 | F10 (0.39) | F10SLC1A3SLC1A2USP5OGT | |
| SCHEMBL640662 | 0.76 | ALDH1A1 (0.43) | F10USP5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL639855 | 0.76 | MGLL (0.35) | F10KDM4EALDH1A1 | |
| SCHEMBL639633 | 0.76 | HTR6 (0.36) | DRD1DRD2F10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528712-B | Substituted benzimidazolone derivatives, medicaments containing them and the use thereof | ABBOTT GMBH & CO KG | 2013-10-30 | — | — | CN | disclosed |
| CN-101528712-A | Substituted benzimidazolone derivatives, medicaments containing them and the use thereof | ABBOTT GMBH & CO KG (DE) | 2009-09-09 | — | — | CN | disclosed |