Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368694 | 1.00 | MCHR1 (0.52) | MCHR1CHRM1HTR2AHRH3POLB | |
| SCHEMBL14368730 | 0.90 | POLB (0.58) | HRH3POLBTP53MAPTCCR3 | |
| SCHEMBL28783273 | 0.90 | POLB (0.58) | HRH3POLBTP53MAPTCCR3 | |
| SCHEMBL14368751 | 0.87 | NPC1 (0.52) | CCR3SIGMAR1HPGD | |
| SCHEMBL27757307 | 0.87 | NPC1 (0.52) | CCR3SIGMAR1HPGD | |
| SCHEMBL14369063 | 0.84 | CCR3 (0.48) | HTR2ACCR3 | |
| SCHEMBL27778278 | 0.83 | CCR3 (0.47) | HTR2ACCR3 | |
| SCHEMBL14368993 | 0.83 | CCR3 (0.47) | HTR2ACCR3 | |
| SCHEMBL14368748 | 0.82 | TP53 (0.48) | POLBTP53SIGMAR1HPGD | |
| SCHEMBL27778439 | 0.82 | TP53 (0.48) | POLBTP53SIGMAR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |