SCHEMBL28784349

SCHEMBL28784349

CCOc1ccc(OS(C)(=O)=O)nc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
PKM P14618 1/20 0.43
GRM5 P41594 1/20 0.42
ALDH1A1 P00352 2/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 2/20 0.39
MAPK1 P28482 2/20 0.39
LMNA P02545 2/20 0.39
CYP1A2 P05177 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29658840 0.79 NQO1 (0.56) NQO1MAPTMAPK1TDP1TSHR
SCHEMBL3822379 0.79 NQO1 (0.56) NQO1MAPTMAPK1TDP1TSHR
SCHEMBL28040973 0.77 NQO1 (0.61) NQO1CA12CA1CA2CA7
SCHEMBL6832597 0.76 NQO1 (0.52) NQO1MAPTTDP1TSHR
SCHEMBL5700546 0.75 NQO1 (0.46) NQO1CA12CA1CA2CA7
SCHEMBL31039780 0.75 NNMT (0.43) CA1CA2MAPTPOLBLMNA
SCHEMBL18035007 0.74 GRM5 (0.49) CA1CA2CA9GRM5ALDH1A1
SCHEMBL6615369 0.73 GRM5 (0.44) CA1CA2CA9GRM5ALDH1A1
SCHEMBL28887396 0.72 CA1 (0.39) CA1CA2CA9PKMALDH1A1
SCHEMBL17541763 0.72 MMP2 (0.35) CA12CA2PKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114725516-A Electrolyte, preparation method thereof and lithium ion battery containing electrolyte 湖北亿纬动力有限公司 2022-07-08 CN claimed