Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22852596 | 0.84 | NNMT (0.42) | NNMTCA1CA2KDM4EPOLB | |
| SCHEMBL22444656 | 0.81 | SLC22A12 (0.43) | NNMTCA1CA2KDM4EPOLB | |
| SCHEMBL29525223 | 0.78 | NNMT (0.48) | NNMTCA1CA2KDM4EMKNK1 | |
| SCHEMBL3816388 | 0.78 | NNMT (0.48) | NNMTCA1CA2KDM4EMKNK1 | |
| SCHEMBL28610470 | 0.76 | SIRT6 (0.46) | NNMTKCNH2TUBB4ATUBBTUBA3C | |
| SCHEMBL28784349 | 0.75 | NQO1 (0.43) | CA1CA2POLBLMNAMAPT | |
| SCHEMBL6941035 | 0.73 | CA1 (0.64) | CA1CA2MAPTCYP2A6 | |
| SCHEMBL1688213 | 0.73 | KCNH2 (0.56) | NNMTKCNH2CA1CA2KDM4E | |
| SCHEMBL27703306 | 0.73 | LMNA (0.51) | KCNH2KDM4EMEN1PABPC1KMT2A | |
| SCHEMBL31428799 | 0.73 | TUBB4A (0.36) | CA2KDM4ETUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978537-A | Pyrazolo [1,5-a ] pyridine derivative, preparation method and application thereof | 上海岱岱投资咨询有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-113508116-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method and application thereof | 察略盛医药科技(上海)有限公司 | 2024-08-13 | — | — | CN | disclosed |