Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1556313 | 0.89 | ALKBH2 (0.73) | HPGDSALKBH2NPC1RAB9AMAPT | |
| SCHEMBL29544594 | 0.89 | ALKBH2 (0.73) | HPGDSALKBH2NPC1RAB9AMAPT | |
| SCHEMBL23846557 | 0.87 | F7 (0.54) | HPGDSALKBH2NPC1RAB9AMAPT | |
| SCHEMBL1554748 | 0.87 | ALKBH2 (0.53) | HPGDSALKBH2NPC1RAB9AMAPT | |
| SCHEMBL12410370 | 0.87 | ALKBH2 (0.53) | HPGDSALKBH2NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL1680337 | 0.86 | ALKBH2 (0.51) | HPGDSALKBH2NPC1RAB9AMAPT | |
| SCHEMBL27862942 | 0.84 | GRM1 (0.54) | HPGDSALKBH2NPC1RAB9AMAPT | |
| SCHEMBL12410371 | 0.83 | HPGDS (0.49) | HPGDSALKBH2NPC1RAB9AMAPT | |
| SCHEMBL18682731 | 0.83 | MKNK1 (0.55) | HPGDSALKBH2NPC1RAB9AMAPT | |
| SCHEMBL7729542 | 0.82 | HPGDS (0.79) | HPGDSALKBH2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |