Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1680337 | 0.98 | ALKBH2 (0.51) | ALKBH2HPGDSPRMT5CYP2A6RIPK2 | |
| SCHEMBL28784681 | 0.87 | HPGDS (0.56) | ALKBH2HPGDSPRMT5CYP2A6RIPK2 | |
| SCHEMBL29544594 | 0.86 | ALKBH2 (0.73) | ALKBH2HPGDSPRMT5CYP2A6NPC1 | |
| SCHEMBL1556313 | 0.86 | ALKBH2 (0.73) | ALKBH2HPGDSPRMT5CYP2A6NPC1 | |
| SCHEMBL23846557 | 0.84 | F7 (0.54) | ALKBH2HPGDSPRMT5CYP2A6RIPK2 | |
| SCHEMBL1554748 | 0.84 | ALKBH2 (0.53) | ALKBH2HPGDSPRMT5CYP2A6RIPK2 | |
| SCHEMBL18016128 | 0.83 | ALKBH2 (0.74) | ALKBH2HPGDSNPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL17981394 | 0.82 | ALKBH2 (0.72) | ALKBH2HPGDSNPC1MAPTRAB9A | |
| SCHEMBL27862942 | 0.82 | GRM1 (0.54) | ALKBH2HPGDSPRMT5CYP2A6RIPK2 | |
| SCHEMBL12410371 | 0.81 | HPGDS (0.49) | ALKBH2HPGDSPRMT5CYP2A6RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488510-B1 | Amides and thioamides as pest control agents | BAYER IP GMBH (DE) | 2017-03-29 | — | — | EP | disclosed |
| US-9066518-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066518-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-07 | — | — | US | disclosed |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-07 | — | — | US | disclosed |
| US-8536204-B2 | Amides and thioamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2013-09-17 | — | — | US | disclosed |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20110118290-A1 | Novel Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| WO-2011045224-A1 | 1- (PYRID-3-YL) -PYRAZOLE AND 1- (PYRIMID-5-YL) -PYRAZOLE AS PESTICIDE | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118290-A1 | Novel Amides and Thioamides as Pesticides | NAAA, AADAC, PTMS | ALKBH2 1036/4885HPGDS 3983/4885PRMT5 579/4885 |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, BCHE | ALKBH2 3095/4885HPGDS 1274/4885PRMT5 2065/4885 |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, BCHE | ALKBH2 3095/4885HPGDS 1274/4885PRMT5 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.