Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082573 | 0.79 | OR51E2 (0.42) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL468822 | 0.79 | MTNR1A (0.44) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL8599982 | 0.77 | RNPEP (0.44) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL542281 | 0.77 | GFPT1 (0.52) | — | |
| SCHEMBL542282 | 0.77 | GFPT1 (0.52) | — | |
| SCHEMBL25345631 | 0.77 | GFPT1 (0.52) | — | |
| SCHEMBL23451094 | 0.75 | MAPT (0.59) | MTNR1AMTNR1BKDM4EMAPTTHRB | |
| SCHEMBL26008141 | 0.75 | MAPT (0.43) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL25356963 | 0.75 | MAPT (0.43) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL26490723 | 0.75 | MAPK1 (0.45) | MTNR1AMTNR1BKDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160040059-A1 | Subterranean Reservoir Treatment Method | SCHLUMBERGER TECHNOLOGY CORP (US) | 2016-02-11 | — | — | US | disclosed |
| US-20160040059-A1 | Subterranean Reservoir Treatment Method | SCHLUMBERGER TECHNOLOGY CORP (US) | 2016-02-11 | — | — | US | disclosed |
| US-20130048283-A1 | Subterranean Reservoir Treatment Method | SCHLUMBERGER TECHNOLOGY CORPORATION | 2013-02-28 | — | — | US | disclosed |
| EP-2002836-B1 | Cyclocondensed azaindoles active as kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL (IT) | 2010-10-20 | — | — | EP | disclosed |
| EP-2002836-A1 | Cyclocondensed azaindoles active as kinase inhibitors | Nerviano Medical Sciences S.r.l. (IT) | 2008-12-17 | — | — | EP | disclosed |