SCHEMBL542282

SCHEMBL542282

CC(=O)NCC(N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GFPT1 Q06210 1/20 0.52
SLC7A5 Q01650 1/20 0.44
CASR P41180 3/20 0.44
GRIK1 P39086 1/20 0.43
PTGS1 P23219 1/20 0.42
SLC7A11 Q9UPY5 1/20 0.42
GGT1 P19440 4/20 0.41
SLC1A3 P43003 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25345631 1.00 GFPT1 (0.52) GFPT1SLC7A5CASRGRIK1PTGS1
SCHEMBL542281 1.00 GFPT1 (0.52) GFPT1SLC7A5CASRGRIK1PTGS1
SCHEMBL1768739 0.84 CASR (0.45) GFPT1SLC7A5CASR
SCHEMBL1768743 0.84 CASR (0.45) GFPT1SLC7A5CASR
SCHEMBL28387960 0.83 KDM4E (0.39) GFPT1CASR
SCHEMBL10280376 0.82 GFPT1 (0.49) GFPT1SLC7A5CASRGRIK1PTGS1
SCHEMBL2716862 0.82 GFPT1 (0.49) GFPT1SLC7A5CASRGRIK1PTGS1
SCHEMBL14381155 0.81 KDM4E (0.37) GFPT1CASR
SCHEMBL19371884 0.81 KDM4E (0.37) GFPT1CASR
SCHEMBL31524073 0.80 CYP2D6 (0.50) GFPT1SLC7A5CASRGRIK1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9101662-B2 Compositions with modulating agents FOAMIX PHARMACEUTICALS LTD. (IL) 2015-08-11 US claimed
US-8795693-B2 Compositions with modulating agents FOAMIX LTD. (IL) 2014-08-05 US claimed
EP-2097065-A2 FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS Foamix Ltd. (IL) 2009-09-09 EP claimed
WO-2008152444-A2 FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS FOAMIX LTD. (US) 2008-12-18 WO claimed
EP-1976873-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS Brystol-Myers Squibb Company (US) 2008-10-08 EP claimed
US-20080206159-A1 Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions FOAMIX LTD. (IL) 2008-08-28 US claimed
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-10-11 US claimed
WO-2007082264-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-07-19 WO claimed
US-12624067-B2 Cyclic peptide, cell scaffold material, cell separating material, and medium FUJIFILM CORPORATION (JP) 2026-05-12 US disclosed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 EP disclosed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 EP disclosed
EP-4540267-B1 CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2026-04-15 EP disclosed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 WO disclosed
CN-113993882-B Cyclic peptides, cell scaffold material, cell separation material and culture medium 富士胶片株式会社 2024-12-17 CN disclosed
US-20070254315-A1 SCREENING FOR NEUROTOXIC AMINO ACID ASSOCIATED WITH NEUROLOGICAL DISORDERS THE INSTITUTE FOR ETHNOMEDICINE (US) 2007-11-01 US disclosed
US-7256002-B2 Screening for neurotoxic amino acid associated with neurological disorders THE INSTITUTE FOR ETHNOMEDICINE (US) 2007-08-14 US disclosed
EP-1664793-A1 NEUROTOXIC AMINO ACID OR NEUROTOXIC DERIVATIVE THEREOF ASSOCIATED WITH NEUROLOGICAL DISORDERS Institute For Ethnomedicine (US) 2006-06-07 EP disclosed
WO-2005019830-A1 NEUROTOXIC AMINO ACID OR NEUROTOXIC DERIVATIVE THEREOF ASSOCIATED WITH NEUROLOGICAL DISORDERS INSTITUTE FOR ETHNOMEDICINE (US) 2005-03-03 WO disclosed
US-20050042686-A1 Neurotoxic amino acid or neurotoxic derivative thereof associated with neurological disorders NATIONAL TROPICAL BOTANICAL GARDEN 2005-02-24 US disclosed
EP-0350163-A2 Renin inhibitory peptides BEECHAM GROUP PLC (GB) 1990-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS GLP1R, GIPR, IAPP GFPT1 1805/4885SLC7A5 2674/4885CASR 803/4885
US-20080206159-A1 Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions CUTA, SLTM, SMO GFPT1 3155/4885SLC7A5 4410/4885CASR 2351/4885
US-12624067-B2 Cyclic peptide, cell scaffold material, cell separating material, and medium ITGB1, ITGAM, ITGA1 GFPT1 1001/4885SLC7A5 392/4885CASR 1181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.