Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.46 |
| ▸ | THRA | P10827 | 8/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28786138 | 0.91 | THRB (0.49) | THRBTHRAPPARAPPARGFFAR4 | |
| SCHEMBL28786149 | 0.84 | THRB (0.56) | THRBTHRAFFAR4LMNAL3MBTL1 | |
| SCHEMBL18002694 | 0.81 | THRB (0.69) | THRBTHRAPPARGFFAR4 | |
| SCHEMBL6855002 | 0.80 | PPARA (0.43) | PPARAPPARGFFAR4OPRK1 | |
| SCHEMBL19920685 | 0.80 | THRB (0.53) | THRBTHRAFFAR4OPRK1OPRM1 | |
| SCHEMBL28786132 | 0.80 | THRB (0.50) | THRBTHRAFFAR4L3MBTL1OPRK1 | |
| SCHEMBL19859389 | 0.78 | THRB (0.56) | THRBTHRAFFAR4LMNA | |
| SCHEMBL28786167 | 0.77 | THRB (0.46) | THRBTHRAFFAR4L3MBTL1 | |
| SCHEMBL19102267 | 0.77 | THRB (0.54) | THRBTHRAFFAR4 | |
| SCHEMBL19920556 | 0.76 | THRB (0.51) | THRBTHRAFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763363-B | Phosphoric acid or phosphate derivative, preparation method thereof and application thereof in medicine | 上海喀露蓝科技有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114763363-A | Phosphoric acid or phosphate ester derivative, preparation method thereof and application thereof in medicine | 上海喀露蓝科技有限公司 | 2022-07-19 | — | — | CN | disclosed |