Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.46 |
| ▸ | THRA | P10827 | 8/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28786132 | 0.85 | THRB (0.50) | THRBTHRAFFAR4MAPTMAPK1 | |
| SCHEMBL282646 | 0.84 | THRB (0.45) | THRBTHRA | |
| SCHEMBL18002694 | 0.83 | THRB (0.69) | THRBTHRAFFAR4 | |
| SCHEMBL29800201 | 0.81 | MAPK1 (0.36) | THRBTHRAFFAR4PTGER1MAPT | |
| SCHEMBL28786138 | 0.80 | THRB (0.49) | THRBTHRAFFAR4 | |
| SCHEMBL23824146 | 0.80 | FFAR4 (0.48) | FFAR4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL19859389 | 0.79 | THRB (0.56) | THRBTHRAFFAR4 | |
| SCHEMBL28786149 | 0.79 | THRB (0.56) | THRBTHRAFFAR4MAPK1L3MBTL1 | |
| SCHEMBL6852831 | 0.79 | KEAP1 (0.36) | THRBTHRAMAPTSTAT3HTT | |
| SCHEMBL282959 | 0.78 | THRB (0.37) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763363-B | Phosphoric acid or phosphate derivative, preparation method thereof and application thereof in medicine | 上海喀露蓝科技有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114763363-A | Phosphoric acid or phosphate ester derivative, preparation method thereof and application thereof in medicine | 上海喀露蓝科技有限公司 | 2022-07-19 | — | — | CN | disclosed |