Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 13/20 | 0.56 |
| ▸ | THRA | P10827 | 12/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19920685 | 0.93 | THRB (0.53) | THRBTHRAESR1FFAR4NPC1 | |
| SCHEMBL19102267 | 0.91 | THRB (0.54) | THRBTHRAFFAR4NPC1MAPK1 | |
| SCHEMBL18002694 | 0.90 | THRB (0.69) | THRBTHRAFFAR4 | |
| SCHEMBL19920556 | 0.89 | THRB (0.51) | THRBTHRAFFAR4NPC1MAPK1 | |
| SCHEMBL19859389 | 0.86 | THRB (0.56) | THRBTHRALMNAFFAR4POLB | |
| SCHEMBL24449952 | 0.86 | THRB (0.55) | THRBTHRA | |
| SCHEMBL19102268 | 0.84 | THRB (0.46) | THRBTHRAL3MBTL1 | |
| SCHEMBL28786148 | 0.84 | THRB (0.46) | THRBTHRALMNAFFAR4L3MBTL1 | |
| SCHEMBL19505434 | 0.83 | THRB (0.75) | THRBTHRA | |
| SCHEMBL18028293 | 0.82 | THRB (0.77) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763363-B | Phosphoric acid or phosphate derivative, preparation method thereof and application thereof in medicine | 上海喀露蓝科技有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114763363-A | Phosphoric acid or phosphate ester derivative, preparation method thereof and application thereof in medicine | 上海喀露蓝科技有限公司 | 2022-07-19 | — | — | CN | disclosed |