Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828341 | 0.84 | APP (0.53) | APPMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23364361 | 0.84 | APP (0.53) | APPMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29874189 | 0.84 | APP (0.53) | APPMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30006266 | 0.83 | APP (0.55) | APPMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27173183 | 0.83 | APP (0.55) | APPMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28786197 | 0.82 | MAPT (0.47) | APPTSHRMAPTSMN1; SMN2NPC1 | |
| SCHEMBL26518067 | 0.79 | APP (0.57) | APPMAPT | |
| SCHEMBL28944764 | 0.77 | APP (0.45) | APPMAPTGAA | |
| SCHEMBL29453158 | 0.76 | MAPT (0.57) | APPMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23364355 | 0.76 | MAPT (0.57) | APPMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728071-A | Compound for degrading TAU protein aggregate and application thereof | 新旭生技股份有限公司 | 2022-07-08 | — | — | CN | disclosed |