Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006266 | 0.89 | APP (0.55) | APPMAPTRAB9ANPC1KDM4E | |
| SCHEMBL27173183 | 0.89 | APP (0.55) | APPMAPTRAB9ANPC1KDM4E | |
| SCHEMBL26518067 | 0.84 | APP (0.57) | APPMAPT | |
| SCHEMBL28786192 | 0.84 | APP (0.52) | APPMAPTRAB9ANPC1KDM4E | |
| SCHEMBL23364361 | 0.83 | APP (0.53) | APPMAPTRAB9ANPC1KDM4E | |
| SCHEMBL29874189 | 0.83 | APP (0.53) | APPMAPTRAB9ANPC1KDM4E | |
| SCHEMBL13394576 | 0.79 | APP (0.62) | APPMAPTMEN1KMT2ASULT1A1 | |
| SCHEMBL14450187 | 0.78 | APP (0.67) | APPMAPTMEN1KMT2ASULT1A1 | |
| SCHEMBL29453199 | 0.78 | APP (0.76) | APPMAPTSMN1; SMN2TP53SULT1A1 | |
| SCHEMBL27173199 | 0.78 | APP (0.76) | APPMAPTSMN1; SMN2TP53SULT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377496-A | Compounds for degrading alpha-synuclein aggregates and uses thereof | 新旭生技股份有限公司 | 2024-01-09 | — | — | CN | disclosed |