Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068583 | 0.81 | PTGS2 (0.40) | PTGS2PTGS1CA12CA1CA9 | |
| SCHEMBL4075622 | 0.74 | PSMD10 (0.38) | CASP3CASP7CA12CA1CA9 | |
| SCHEMBL4815560 | 0.74 | ALDH1A1 (0.48) | CA12CA1CA9ALDH1A1PSMD10 | |
| SCHEMBL8483813 | 0.74 | ALDH1A1 (0.48) | CA12CA1CA9ALDH1A1PSMD10 | |
| SCHEMBL4954181 | 0.74 | ALDH1A1 (0.48) | CA12CA1CA9ALDH1A1PSMD10 | |
| SCHEMBL8484861 | 0.74 | ALDH1A1 (0.48) | CA12CA1CA9ALDH1A1PSMD10 | |
| SCHEMBL4812770 | 0.74 | ALDH1A1 (0.48) | CA12CA1CA9ALDH1A1PSMD10 | |
| SCHEMBL4951882 | 0.74 | ALDH1A1 (0.48) | CA12CA1CA9ALDH1A1PSMD10 | |
| SCHEMBL11050599 | 0.74 | ALDH1A1 (0.48) | CA12CA1CA9ALDH1A1PSMD10 | |
| SCHEMBL3545668 | 0.74 | ALDH1A1 (0.48) | CA12CA1CA9ALDH1A1PSMD10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728071-A | Compound for degrading TAU protein aggregate and application thereof | 新旭生技股份有限公司 | 2022-07-08 | — | — | CN | disclosed |