Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28790189 | 0.80 | APP (0.43) | ALOX15APPPPARGLOXL2STS | |
| SCHEMBL28290282 | 0.78 | PPARG (0.60) | MAPTNPC1RAB9ATP53CYP3A4 | |
| SCHEMBL28007144 | 0.72 | FLT3 (0.44) | MAPTNPC1HPGDMEN1KMT2A | |
| SCHEMBL27610326 | 0.72 | LOXL2 (0.42) | MAPTHPGDMEN1KMT2AKDM4E | |
| Ethoxycarbonyl Group SCHEMBL28786244 | 0.71 | DYRK1A (0.46) | MAPTTP53CYP3A4HPGDMEN1 | |
| SCHEMBL27823376 | 0.70 | ESR1 (0.43) | ACHEPPARG | |
| SCHEMBL7573134 | 0.69 | ALOX15 (0.81) | ALOX15MAPTNPC1RAB9ATP53 | |
| SCHEMBL28031544 | 0.68 | NOTUM (0.42) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7673826 | 0.67 | ALOX15 (0.92) | ALOX15MAPTNPC1RAB9ATP53 | |
| SCHEMBL18397817 | 0.67 | ALOX15 (0.64) | ALOX15MAPTNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101977505-A | Farnesoid x receptor agonists | SMITHKLINE BEECHAM CORP | 2011-02-16 | — | — | CN | disclosed |