Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28790189 | 0.82 | APP (0.43) | PPARGSTS | |
| SCHEMBL27610326 | 0.82 | LOXL2 (0.42) | PPARGCYP11B1CYP11B2HPGDCA12 | |
| SCHEMBL28907602 | 0.80 | LOXL2 (0.50) | HPGDSMN1; SMN2CYP19A1 | |
| SCHEMBL28754013 | 0.78 | LOXL2 (0.59) | PPARGHPGDSMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL28786246 | 0.78 | ALOX15 (0.49) | PPARGNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL292258 | 0.76 | PPARG (0.69) | PPARGCYP11B1CYP11B2SIGMAR1NPC1 | |
| SCHEMBL30694898 | 0.76 | PPARG (0.69) | PPARGCYP11B1CYP11B2SIGMAR1NPC1 | |
| SCHEMBL3715533 | 0.76 | PPARG (0.69) | PPARGCYP11B1CYP11B2SIGMAR1NPC1 | |
| SCHEMBL19925815 | 0.76 | PPARG (0.69) | PPARGCYP11B1CYP11B2SIGMAR1NPC1 | |
| Flidersiachromone SCHEMBL5826185 | 0.75 | PPARG (1.00) | PPARGCYP11B1CYP11B2SIGMAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641864-A | ANTI-INFECTIVE AGENTS | 邓迪大学 | 2019-04-16 | — | — | CN | disclosed |