Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 7/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983559 | 0.92 | PTK2 (0.39) | PTK2HTR4ROCK2MELKSSTR1 | |
| Tert-Butyl Formate SCHEMBL27802920 | 0.91 | SSTR1 (0.36) | PTK2HTR4ROCK2MELKSSTR1 | |
| Ethoxycarbonyl Group SCHEMBL27802937 | 0.90 | KDM1A (0.38) | PTK2HTR4DGAT2KDM1A | |
| SCHEMBL987097 | 0.85 | CNR1 (0.38) | HTR7BTKCNR2 | |
| SCHEMBL987096 | 0.85 | CNR1 (0.38) | HTR7BTKCNR2 | |
| SCHEMBL982008 | 0.85 | BTK (0.40) | PTK2BTK | |
| SCHEMBL984646 | 0.83 | ACKR3 (0.41) | PTK2HTR4KDM1A | |
| SCHEMBL984599 | 0.83 | BTK (0.39) | KDM1ABTK | |
| SCHEMBL986013 | 0.83 | MEN1 (0.46) | — | |
| Tert-Butyl Formate SCHEMBL27823657 | 0.83 | SYK (0.36) | PTK2HTR4KDM1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959890-B | Pyrrolopyrimidine carboxamides | NYCOMED GMBH | 2013-10-30 | — | — | CN | disclosed |
| CN-101959890-A | Pyrrolopyrimidine carboxamides | NYCOMED GMBH | 2011-01-26 | — | — | CN | disclosed |