Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 7/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 4/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853202 | 0.93 | SYK (0.39) | SYKAURKBINCENPBRD4PDE10A | |
| SCHEMBL4792958 | 0.85 | SYK (0.39) | SYKAURKBINCENPPDE10ATSHR | |
| SCHEMBL2851460 | 0.80 | ALDH1A1 (0.37) | SYKAURKBGSTP1CYP2C19CYP2C9 | |
| SCHEMBL2849017 | 0.74 | GSTP1 (0.42) | GSTP1HPD | |
| SCHEMBL2853278 | 0.72 | ALDH1A1 (0.39) | SYKAURKB | |
| SCHEMBL2878634 | 0.72 | CYP2C19 (0.39) | BRD4PDE10AMAT2ACYP2C19CYP2C9 | |
| SCHEMBL2849065 | 0.70 | GSTP1 (0.40) | GSTP1 | |
| SCHEMBL2853925 | 0.70 | PDGFRB (0.38) | SYKBRD4GSTP1PPARD | |
| SCHEMBL2850939 | 0.67 | MPO (0.41) | PPARD | |
| SCHEMBL2853209 | 0.66 | L3MBTL1 (0.38) | SYKAURKBINCENPPDE10APPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924558-B1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2010-01-13 | — | — | EP | disclosed |
| EP-1924558-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007032016-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-03-22 | — | — | WO | disclosed |