Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785697 | 1.00 | KDM4E (0.33) | KDM4EMAPTHPGDHTTHSD17B10 | |
| SCHEMBL1763340 | 0.79 | GABRP (0.34) | KDM4E | |
| SCHEMBL29141389 | 0.78 | — | — | |
| SCHEMBL30013736 | 0.78 | — | — | |
| SCHEMBL21552078 | 0.77 | SIRT6 (0.35) | — | |
| SCHEMBL31577769 | 0.76 | KDM4E (0.41) | KDM4EMAPTHPGD | |
| SCHEMBL30225249 | 0.76 | NOS3 (0.36) | — | |
| SCHEMBL502805 | 0.76 | KDM4E (0.41) | KDM4EMAPTHPGD | |
| SCHEMBL31388772 | 0.74 | — | — | |
| SCHEMBL2961237 | 0.73 | CYP2D6 (0.40) | KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117337193-A | combination therapy | 基因泰克公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-114786778-A | Therapeutic compounds | 基因泰克公司 | 2022-07-22 | — | — | CN | disclosed |