Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1577273 | 0.81 | NOTUM (0.50) | RECQLF7F3SARM1SIRT2 | |
| Hydrochloric Acid SCHEMBL17785084 | 0.79 | NOTUM (0.49) | RECQLF7F3SARM1SIRT2 | |
| SCHEMBL1520692 | 0.78 | HTT (0.53) | SIRT2GAAHPGDALDH1A1RAB9A | |
| SCHEMBL8980796 | 0.74 | CHRNB2 (0.42) | RECQLGAAHPGDKCNA5ALDH1A1 | |
| SCHEMBL17968066 | 0.73 | F7 (0.44) | RECQLF7F3SARM1SIRT2 | |
| SCHEMBL5633185 | 0.73 | F7 (0.52) | RECQLF7F3SARM1SIRT2 | |
| SCHEMBL8803617 | 0.72 | F7 (0.43) | RECQLF7F3SARM1SIRT2 | |
| SCHEMBL965251 | 0.72 | NOTUM (0.51) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL3576501 | 0.72 | NOTUM (0.51) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL8666511 | 0.72 | F7 (0.50) | RECQLF7F3SARM1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101684084-A | Tetracycline compounds containing carbamido | SHANDONG XUANZHU MEDICINE TECH | 2010-03-31 | — | — | CN | claimed |
| CN-101684084-A | Tetracycline compounds containing carbamido | SHANDONG XUANZHU MEDICINE TECH | 2010-03-31 | — | — | CN | disclosed |