Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785681 | 1.00 | LMNA (0.36) | LMNAHTTTSHRKDM4EMAPT | |
| SCHEMBL114947 | 0.77 | — | — | |
| SCHEMBL21552099 | 0.76 | LMNA (0.36) | LMNAHTTTSHRKDM4EMAPT | |
| SCHEMBL31319231 | 0.76 | EPHX2 (0.34) | LMNA | |
| SCHEMBL23162812 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL5179044 | 0.73 | LMNA (0.38) | LMNAHTTTSHRKDM4EMAPT | |
| SCHEMBL23162814 | 0.73 | — | — | |
| SCHEMBL2213452 | 0.70 | CYP3A4 (0.33) | — | |
| SCHEMBL1671404 | 0.69 | CYP2D6 (0.32) | — | |
| SCHEMBL29782963 | 0.69 | CYP2D6 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114786778-A | Therapeutic compounds | 基因泰克公司 | 2022-07-22 | — | — | CN | disclosed |