Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935645 | 0.79 | NAPRT (0.37) | TSHRKCNH2 | |
| SCHEMBL12502917 | 0.77 | P2RX7 (0.34) | LMNAHTTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL28786396 | 0.76 | LMNA (0.36) | LMNAHTTTSHRKDM4EMAPT | |
| SCHEMBL29785681 | 0.76 | LMNA (0.36) | LMNAHTTTSHRKDM4EMAPT | |
| SCHEMBL4753484 | 0.76 | KDM4E (0.35) | LMNAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL31319231 | 0.75 | EPHX2 (0.34) | LMNA | |
| SCHEMBL1255442 | 0.73 | SLC6A2 (0.36) | KDM4E | |
| SCHEMBL14120504 | 0.73 | APLNR (0.37) | TSHRKDM4EMAPT | |
| SCHEMBL5179044 | 0.73 | LMNA (0.38) | LMNAHTTTSHRKDM4EMAPT | |
| SCHEMBL691136 | 0.72 | KDM4E (0.41) | LMNAHTTKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790876-B1 | ENDOPARASITIC DEPSIPEPTIDES | ZOETIS SERVICES LLC (US) | 2025-04-30 | — | — | EP | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| US-20220323540-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-10-13 | — | — | US | disclosed |
| EP-3790876-A1 | ENDOPARASITIC DEPSIPEPTIDES | Zoetis Services LLC (US) | 2021-03-17 | — | — | EP | disclosed |
| CN-112384511-A | Endoparasitic depsipeptides | 硕腾服务有限责任公司 | 2021-02-19 | — | — | CN | disclosed |
| WO-2019217449-A1 | ENDOPARASITIC DEPSIPEPTIDES | ZOETIS SERVICES LLC (US) | 2019-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11771738-B2 | Endoparasitic depsipeptides | VIP, PREP, VIPR1 | LMNA 2449/4885HTT 3137/4885TSHR 1643/4885 |
| US-20220323540-A1 | Endoparasitic Depsipeptides | VIP, PREP, VIPR1 | LMNA 2449/4885HTT 3137/4885TSHR 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.