Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711712 | 0.94 | HTR1A (0.44) | HTR1AHTR2AHTR7HTR6PTGER3 | |
| SCHEMBL3700555 | 0.92 | HTR1A (0.48) | HTR1AHTR2AHTR7HTR6PTGER3 | |
| Hydrochloric Acid SCHEMBL3697520 | 0.91 | HTR1A (0.47) | HTR1AHTR2AHTR7HTR6PTGER3 | |
| SCHEMBL27828003 | 0.89 | CIT (0.41) | PTGER3P2RY1HTR3EHTR3BHTR3A | |
| SCHEMBL28790701 | 0.88 | HTR1A (0.42) | HTR1AHTR2AHTR7HTR6PTGER3 | |
| SCHEMBL3695061 | 0.86 | MEN1 (0.50) | FGFR1FGFR4MAPTMEN1KMT2A | |
| SCHEMBL3698624 | 0.86 | PKM (0.47) | HTR1AHTR2AHTR7HTR6FGFR1 | |
| SCHEMBL3709404 | 0.86 | PTGER3 (0.49) | PTGER3FGFR1FGFR4MAPTMEN1 | |
| SCHEMBL3699567 | 0.86 | PTGER3 (0.47) | HTR1AHTR2AHTR7PTGER3P2RY1 | |
| SCHEMBL15053425 | 0.86 | MAPT (0.40) | HTR1AHTR2AHTR7HTR6DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102066372-A | 5, 6-membered heteroaryl bicyclic compounds containing a urea group as kinase inhibitors | ASCEPION PHARMACEUTICALS INC | 2011-05-18 | — | — | CN | claimed |
| CN-102066372-A | 5, 6-membered heteroaryl bicyclic compounds containing a urea group as kinase inhibitors | ASCEPION PHARMACEUTICALS INC | 2011-05-18 | — | — | CN | disclosed |