Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27829294 | 0.82 | GRM6 (0.34) | ALDH1A1HSD17B10CTSSCTSKPPARG | |
| SCHEMBL27829334 | 0.81 | CTSK (0.37) | CTSSCTSKCYP2C19MEN1KMT2A | |
| SCHEMBL1919827 | 0.79 | CYP2C19 (0.43) | KIF11CYP2C19MEN1KMT2ANPC1 | |
| SCHEMBL6368377 | 0.77 | ALDH1A1 (0.42) | KDM4EALDH1A1HSD17B10CTSSCTSK | |
| SCHEMBL28395772 | 0.76 | CYP3A4 (0.40) | CTSSCTSKKIF11PPARGPPARA | |
| SCHEMBL28787489 | 0.76 | CYP3A4 (0.40) | CTSSCTSKKIF11PPARGPPARA | |
| SCHEMBL28543672 | 0.74 | CYP2C9 (0.42) | CTSSCTSKKIF11CYP2C9CYP2C19 | |
| SCHEMBL7945062 | 0.73 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10CTSSCTSK | |
| SCHEMBL7319969 | 0.71 | ALDH1A1 (0.36) | KDM4EALDH1A1HSD17B10CTSSCTSK | |
| SCHEMBL27487742 | 0.71 | CTSS (0.47) | KDM4EALDH1A1HSD17B10CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083793-A | Protease inhibitors | AMBRILIA BIOPHARMA INC | 2011-06-01 | — | — | CN | disclosed |