Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24421824 | 0.81 | MAPT (0.87) | MAPTALDH1A1KMT2AHPGDUSP2 | |
| SCHEMBL22606166 | 0.79 | ALDH1A1 (0.83) | MAPTALDH1A1KMT2AHPGDUSP2 | |
| SCHEMBL16906206 | 0.74 | MAPT (0.74) | MAPTALDH1A1KMT2AHPGDUSP2 | |
| SCHEMBL9445166 | 0.74 | MAPT (0.74) | MAPTALDH1A1KMT2AHPGDUSP2 | |
| SCHEMBL16480419 | 0.74 | MAPT (0.52) | MAPTALDH1A1KMT2AHPGDGAA | |
| SCHEMBL15448162 | 0.74 | MAPT (0.72) | MAPTALDH1A1KMT2AHPGD | |
| SCHEMBL7017325 | 0.72 | MAPT (0.72) | MAPTALDH1A1KMT2AHPGDUSP2 | |
| SCHEMBL6129230 | 0.70 | ALDH1A1 (0.68) | MAPTALDH1A1KMT2AHPGDUSP2 | |
| SCHEMBL12437118 | 0.69 | MAPT (0.46) | MAPTALDH1A1KMT2AHPGDUSP2 | |
| SCHEMBL21120669 | 0.68 | MAPT (0.43) | MAPTALDH1A1KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046598-A | Novel donor-acceptor fluorene scaffolds : a process and uses thereof | COUNCIL SCIENT IND RES | 2011-05-04 | — | — | CN | disclosed |