Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1198043 | 0.80 | CYP1A2 (0.42) | L3MBTL1ALDH1A1TDP1MEN1NPC1 | |
| SCHEMBL1198045 | 0.80 | CYP1A2 (0.42) | L3MBTL1ALDH1A1TDP1MEN1NPC1 | |
| SCHEMBL28578166 | 0.79 | L3MBTL1 (0.62) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL27806599 | 0.77 | L3MBTL1 (0.56) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL27806602 | 0.76 | L3MBTL1 (0.59) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL4022892 | 0.75 | L3MBTL1 (0.62) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL31681673 | 0.75 | L3MBTL1 (0.67) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL12890301 | 0.74 | GAA (0.32) | ALDH1A1TDP1MEN1NPC1HTT | |
| SCHEMBL18569795 | 0.74 | L3MBTL1 (0.49) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL29954606 | 0.73 | L3MBTL1 (0.65) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102056907-B | Heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL | 2014-12-31 | — | — | CN | disclosed |
| CN-102056907-A | Heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL | 2011-05-11 | — | — | CN | disclosed |