Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18569555 | 0.81 | GRM2 (0.40) | L3MBTL1HSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL27806599 | 0.80 | L3MBTL1 (0.56) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL28578166 | 0.76 | L3MBTL1 (0.62) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL28790604 | 0.74 | L3MBTL1 (0.53) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL27806602 | 0.73 | L3MBTL1 (0.59) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL4022892 | 0.72 | L3MBTL1 (0.62) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL31681673 | 0.71 | L3MBTL1 (0.67) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL23907233 | 0.71 | L3MBTL1 (0.49) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL23907231 | 0.71 | L3MBTL1 (0.49) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 | |
| SCHEMBL29954606 | 0.70 | L3MBTL1 (0.65) | L3MBTL1PLA2G4AALKBH2HPGDSHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984091-B1 | DIHYDROPYRIDO PYRIMIDINE COMPOUNDS AS AUTOTAXIN INHIBITORS | LILLY CO ELI (US) | 2017-03-01 | — | — | EP | disclosed |