Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18737242 | 0.91 | BCL2 (0.44) | PTGS1PTGS2BCL2MCL1 | |
| SCHEMBL31063437 | 0.85 | CA12 (0.45) | PDE2APTGS1PTGS2ADRA1A | |
| SCHEMBL8241491 | 0.85 | CA12 (0.45) | PDE2APTGS1PTGS2ADRA1A | |
| SCHEMBL16886107 | 0.85 | ALDH1A1 (0.40) | PDE2APTGS1PTGS2CARM1TRPA1 | |
| SCHEMBL5018932 | 0.83 | ALDH1A1 (0.43) | PDE2APTGS1PTGS2CARM1 | |
| SCHEMBL12883118 | 0.82 | PDE2A (0.42) | PDE2APTGS1PTGS2CARM1KCNH2 | |
| SCHEMBL18119645 | 0.82 | NQO1 (0.48) | PDE2APTGS2CARM1 | |
| SCHEMBL12883103 | 0.80 | PDE2A (0.63) | PDE2A | |
| SCHEMBL10000937 | 0.79 | THRB (0.40) | THRATHRBBCL2MCL1NR4A1 | |
| SCHEMBL20791990 | 0.79 | MAOA (0.44) | PDE2ACARM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102056897-A | Sulfonamide compound and application thereof | ASAHI KASEI PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |