Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1313251 | 0.83 | PIM1 (0.37) | PIM1PIM3PIM2NOTUMPARP1 | |
| SCHEMBL1313864 | 0.69 | ALOX15 (0.37) | — | |
| SCHEMBL17104265 | 0.65 | CHRM1 (0.34) | — | |
| SCHEMBL1312777 | 0.63 | PARP1 (0.35) | PIM1PIM3PIM2PARP1 | |
| SCHEMBL1313751 | 0.61 | PARP1 (0.34) | PIM1PIM3PIM2PARP1 | |
| SCHEMBL1313248 | 0.60 | NOTUM (0.31) | NOTUMBRD4 | |
| SCHEMBL4637505 | 0.59 | TDP1 (0.42) | NOTUMFEN1BRD4 | |
| Hydrochloric Acid SCHEMBL6147214 | 0.57 | TDP1 (0.45) | NOTUMFEN1BRD4TLR8TLR7 | |
| SCHEMBL505815 | 0.57 | GABRA5 (0.48) | MAOA | |
| Hydrochloric Acid SCHEMBL1018925 | 0.56 | GABRA5 (0.47) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102066362-A | Dihydroindolinone derivatives | SHANGHAI INST PHARM INDUSTRY | 2011-05-18 | — | — | CN | disclosed |