Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1313862 | 0.81 | ALOX15 (0.36) | — | |
| SCHEMBL1313251 | 0.76 | PIM1 (0.37) | NOTUMBRD4 | |
| SCHEMBL1313749 | 0.72 | — | — | |
| SCHEMBL1313787 | 0.68 | ADRA2A (0.37) | — | |
| SCHEMBL1313864 | 0.63 | ALOX15 (0.37) | — | |
| SCHEMBL4637505 | 0.62 | TDP1 (0.42) | NOTUMBRD4 | |
| Hydrochloric Acid SCHEMBL6147214 | 0.60 | TDP1 (0.45) | NOTUMBRD4 | |
| SCHEMBL28790889 | 0.60 | PIM1 (0.35) | NOTUMBRD4 | |
| SCHEMBL3030276 | 0.59 | ADH1B (0.61) | BRD4 | |
| SCHEMBL19222864 | 0.53 | CRHR1 (0.40) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292613-B1 | DIHYDROINDOLINONE DERIVATIVES | SHANGHAI INST PHARM INDUSTRY (CN) | 2015-09-30 | — | — | EP | disclosed |
| US-8829039-B2 | Dihydroindolinone derivatives | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2014-09-09 | — | — | US | disclosed |
| US-20110275671-A1 | DIHYDROINDOLINONE DERIVATIVES | Shanghai Institute of Pharmaceutical Indusrty (CN) | 2011-11-10 | — | — | US | disclosed |
| EP-2292613-A1 | DIHYDROINDOLINONE DERIVATIVES | Shanghai Institute of Pharmaceutical Industry (CN) | 2011-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275671-A1 | DIHYDROINDOLINONE DERIVATIVES | LCK, CDK5, ABL1 | NOTUM 2441/4885BRD4 1639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.