SCHEMBL28790949

SCHEMBL28790949

C=CC(=O)OCCC[Si](C)(C(C)C)C(C)C

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.55
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 2/20 0.55
HPGD P15428 1/20 0.55
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 2/20 0.39
ATM Q13315 1/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26187833 0.82 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL308812 0.82 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1681567 0.80 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9064667 0.80 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3628945 0.80 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2496765 0.80 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL15700685 0.80 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL141029 0.80 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL230446 0.80 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9313444 0.79 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112105659-B Statistical copolymer latex, use thereof, and method for producing statistical copolymer latex 电化株式会社 2023-05-12 CN disclosed
CN-114806316-A Exterior wall, coating composition for building exterior, and laminate 日信化学工业株式会社 2022-07-29 CN disclosed
CN-114806315-A Coating composition for furniture and building interior, and laminate 日信化学工业株式会社 2022-07-29 CN disclosed