SCHEMBL230446

SCHEMBL230446

C=CC(=O)OCCC[Si](C)(C)OC(C)C

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 2/20 0.52
HPGD P15428 1/20 0.51
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 2/20 0.37
ATM Q13315 1/20 0.34
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HCAR2 Q8TDS4 2/20 0.31
TDP1 Q9NUW8 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30285286 0.94 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL141029 0.87 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL133590 0.85 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL332090 0.83 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL853573 0.83 ATM (0.41) TSHRALDH1A1CYP3A4HPGDATM
SCHEMBL28009740 0.82 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16301383 0.82 TSHR (0.43) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL374776 0.81 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL81411 0.81 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7508187 0.81 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
US-20250032366-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-01-30 US disclosed
US-20250009607-A1 DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE KURARAY NORITAKE DENTAL INC. (JP) 2025-01-09 US disclosed
WO-2024253204-A1 CURABLE DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-12-12 WO disclosed
EP-4464301-A1 DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER Kuraray Noritake Dental Inc. (JP) 2024-11-20 EP disclosed
EP-4445891-A1 DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2024-10-16 EP disclosed
CN-118338879-A Curable composition for dental use 可乐丽则武齿科株式会社 2024-07-12 CN disclosed
US-11787891-B2 Modified block copolymer composition ZEON CORPORATION (JP) 2023-10-17 US disclosed
WO-2023136337-A1 DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER クラレノリタケデンタル株式会社 2023-07-20 WO disclosed
WO-2023106419-A1 DENTAL CURABLE COMPOSITION クラレノリタケデンタル株式会社 2023-06-15 WO disclosed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed
US-6566549-B1 Forming oligomers of vinyl acetate and oligomers of vinyl alcohol; fully saturated and terminally unsaturated oligomers ROHM AND HAAS COMPANY 2003-05-20 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed
US-20020111448-A1 Continuous polymerization process and products therefrom GREENBLATT GARY DAVID (US) 2002-08-15 US disclosed
US-20020082371-A1 Continuous polymerization process and products therefrom GREENBLATT GARY DAVID (US) 2002-06-27 US disclosed
EP-1010706-A2 Continuous polymerization process and products therefrom ROHM AND HAAS COMPANY (US) 2000-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885CYP3A4 3126/4885
US-20250032366-A1 DENTAL CURABLE COMPOSITION H1-0, COL1A1, CHAF1B TSHR 4352/4885ALDH1A1 1530/4885CYP3A4 3913/4885
US-20250009607-A1 DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE CAD, SEM1, CAPZA1 TSHR 3083/4885ALDH1A1 382/4885CYP3A4 4215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.