Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678955 | 1.00 | MGLL (0.33) | MGLLKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29679222 | 0.79 | MAOA (0.37) | KDM4EALDH1A1CYP1A2CYP3A4MAOA | |
| SCHEMBL28792328 | 0.79 | MAOA (0.37) | KDM4EALDH1A1CYP1A2CYP3A4MAOA | |
| SCHEMBL29876849 | 0.78 | MAOA (0.36) | KDM4EALDH1A1CYP1A2CYP3A4MAOA | |
| SCHEMBL28792357 | 0.76 | MAOB (0.34) | KDM4EALDH1A1CYP1A2CYP3A4MAOA | |
| SCHEMBL29678743 | 0.76 | MAOB (0.34) | KDM4EALDH1A1CYP1A2CYP3A4MAOA | |
| SCHEMBL8440636 | 0.68 | MAOA (0.46) | MGLLKDM4EALDH1A1MAOA | |
| SCHEMBL29953443 | 0.67 | MGLL (0.43) | MGLLKDM4EALDH1A1 | |
| SCHEMBL14197691 | 0.65 | CA1 (0.38) | KDM4EALDH1A1CYP1A2CYP3A4MAOA | |
| SCHEMBL4450085 | 0.65 | PIM1 (0.56) | CYP1A2MAOAEGFRPDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761410-B | Pyrrolopyrimidinone compounds and application thereof | 广州必贝特医药股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-114761410-A | Pyrrolopyrimidinone compounds and application thereof | 广州必贝特医药股份有限公司 | 2022-07-15 | — | — | CN | disclosed |