Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497798 | 0.84 | MEN1 (0.41) | MEN1KMT2AALDH1A1MAPTALOX15 | |
| SCHEMBL19974223 | 0.75 | KMT2A (0.50) | MEN1KMT2AALDH1A1MAPTALOX15 | |
| SCHEMBL9005236 | 0.73 | HDAC8 (0.48) | MEN1KMT2AALDH1A1MAPTHTT | |
| Cyclohexene SCHEMBL11229986 | 0.71 | GRM4 (0.43) | ALDH1A1 | |
| SCHEMBL6965651 | 0.71 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1MAPTALOX15 | |
| SCHEMBL2128104 | 0.71 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1MAPTALOX15 | |
| SCHEMBL31299205 | 0.71 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1MAPTALOX15 | |
| SCHEMBL2879227 | 0.70 | GRM4 (0.49) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL9493278 | 0.70 | GRM4 (0.49) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL9493282 | 0.70 | GRM4 (0.49) | MEN1KMT2AALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060159772-A1 | Fungicidal compositions | ISAGRO S.P.A. (IT) | 2006-07-20 | — | — | US | claimed |
| EP-1852428-B1 | 4-CYCLOPROPYL-1,2,3-THIADIAZOLE COMPOUND, AGROHORTICULTURAL PLANT DISEASE CONTROLLING AGENT AND METHOD OF USING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2012-05-16 | — | — | EP | disclosed |
| CN-101128445-B | 4-cyclopropyl-1,2,3-thiadiazole derivative, agrohorticultural plant disease controlling agent, and method for using the same | NIHON NOHYAKU CO LTD | 2012-01-18 | — | — | CN | disclosed |
| US-7786040-B2 | 4-cyclopropyl-1,2,3,-thiadiazole compound, agrohorticultural plant disease controlling agent and method of using the same | NIHON NOHYAKU CO., LTD. (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20100009853-A1 | PARASITIC PLANT CONTROL AGENT AND USE THEREOF | NIHON NOHYAKU CO., LTD (JP) | 2010-01-14 | — | — | US | disclosed |
| US-20080200457-A1 | 4-Cyclopropyl-1,2,3,-Thiadiazole Compound, Agrohorticultural Plant Disease Controlling Agent And Method Of Using The Same | NIHON NOHYAKU CO., LTD. (JP) | 2008-08-21 | — | — | US | disclosed |
| EP-1852428-A1 | 4-CYCLOPROPYL-1,2,3-THIADIAZOLE COMPOUND, AGROHORTICULTURAL PLANT DISEASE CONTROLLING AGENT AND METHOD OF USING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |
| US-20060159772-A1 | Fungicidal compositions | ISAGRO S.P.A. (IT) | 2006-07-20 | — | — | US | disclosed |
| EP-1175834-A1 | METHOD OF THE UTILIZATION OF BACTERICIDAL COMPOSITION | Nihon Nohyaku Co., Ltd. (JP) | 2002-01-30 | — | — | EP | disclosed |
| EP-0301613-B1 | THIAZOLE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-07-10 | — | — | EP | disclosed |
| US-4889863-A | NONPHYTOTOXIC; SEEDS, SOILS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200457-A1 | 4-Cyclopropyl-1,2,3,-Thiadiazole Compound, Agrohorticultural Plant Disease Controlling Agent And Method Of Using The Same | CBR3, CBR1, OSR1 | MEN1 3761/4885KMT2A 2053/4885ALDH1A1 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.