SCHEMBL9497798

SCHEMBL9497798

O=C(NSC(Cl)(Cl)C(Cl)Cl)C1CC=CCC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
ESR2 Q92731 1/20 0.41
HSD17B10 Q99714 1/20 0.41
RAB9A P51151 1/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2879229 0.84 MEN1 (0.45) MEN1ALDH1A1MAPTALOX15HTT
SCHEMBL8525828 0.74
SCHEMBL10374071 0.73 GRM4 (0.44)
SCHEMBL8733415 0.73 GRM4 (0.44)
SCHEMBL9135943 0.73 GRM4 (0.44)
SCHEMBL7635327 0.71
SCHEMBL19974223 0.67 KMT2A (0.50) MEN1ALDH1A1MAPTALOX15HTT
SCHEMBL6965651 0.67 ALDH1A1 (0.53) MEN1ALDH1A1MAPTALOX15HTT
SCHEMBL31299205 0.67 ALDH1A1 (0.53) MEN1ALDH1A1MAPTALOX15HTT
SCHEMBL2128104 0.67 ALDH1A1 (0.53) MEN1ALDH1A1MAPTALOX15HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5212197-A Agriculture DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1993-05-18 US disclosed
EP-0508527-A1 New fungicidally active pyrazole compounds UNIROYAL CHEMICAL COMPANY, Inc. (US) 1992-10-14 EP disclosed
EP-0269141-B1 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1992-09-16 EP disclosed
EP-0301613-B1 THIAZOLE COMPOUNDS HAVING FUNGICIDAL ACTIVITY DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1991-07-10 EP disclosed
EP-0270138-B1 SUBSTITUTED 2-PHENYLIMINO-OXAZOLIDINE COMPOUNDS HAVING HERBICIDAL ACTIVITY DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1991-05-29 EP disclosed
US-4994485-A Seed and soil fungi, bacteria DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1991-02-19 US disclosed
EP-0234622-B1 NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1990-06-27 EP disclosed
US-4927452-A 1-carbonyl-2-pyrazoline derivatives having herbicidal activity DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1990-05-22 US disclosed
US-4889863-A NONPHYTOTOXIC; SEEDS, SOILS DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1989-12-26 US disclosed
US-4854961-A Substituted 2-phenylimino-oxazolidine compounds having herbicidal activity DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1989-08-08 US disclosed
US-4379157-A Sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1983-04-05 US disclosed
US-4374143-A AS FUNGICIDES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1983-02-15 US disclosed
US-4350706-A MITICIDES, LARVICIDES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1982-09-21 US disclosed
EP-0001663-B1 NOVEL 2-ARYLAMINO-HEXAHYDROPYRIMIDINES AND -IMIDAZOLIDINES, SALTS AND COMPLEXES THEREOF, METHOD OF PREPARING THE NOVEL COMPOUNDS AND FUNGICIDAL COMPOSITIONS WHICH CONTAIN THE NOVEL COMPOUNDS DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1982-05-12 EP disclosed
EP-0041298-A2 Composition for inhibiting or preventing the development of suckers in tobacco plants DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1981-12-09 EP disclosed
US-4286983-A INCLUDING COMPOUNDS OF THE N-PHENYL-N',N'-DIETHYL ALKYLENEDIAMINE TYPE DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1981-09-01 US disclosed
EP-0033984-A1 New sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1981-08-19 EP disclosed
EP-0031173-A1 New nitrothiophenes, method of preparing the new compounds, as well as fungicidal and/or bactericidal compositions on the basis of the new compounds DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1981-07-01 EP disclosed
EP-0021506-A2 New pyrazoline derivatives, method of preparing the new compounds, as well as insecticidal composition on the basis of these new compounds DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1981-01-07 EP disclosed
US-4221801-A 2-CYANO-5-NITRO-THIAZOLE DUPHAR INTERNATIONAL RESEARCH (NL) 1980-09-09 US disclosed