SCHEMBL28793909

SCHEMBL28793909

CC(=O)Oc1ccc2[nH]c(C(C)=O)c(CCN)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.50
HTR1D P28221 3/20 0.50
HSD17B10 Q99714 3/20 0.48
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
POLB P06746 1/20 0.47
MDM2 Q00987 1/20 0.47
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
NQO2 P16083 1/20 0.44
TRPM8 Q7Z2W7 1/20 0.44
MTNR1A P48039 7/20 0.43
MTNR1B P49286 7/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPK1 P28482 1/20 0.43
HTR7 P34969 1/20 0.43
HTR3A P46098 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27846878 0.88 KDM4E (0.49) HTR1DHSD17B10KDM4EALDH1A1HPGD
SCHEMBL2403262 0.88 HTR1D (0.65) HTR6HTR1DHSD17B10KDM4EALDH1A1
SCHEMBL27915772 0.75 ALDH1A1 (0.45) HTR1DHSD17B10KDM4EALDH1A1HPGD
SCHEMBL16716149 0.75 HTR1D (0.61) HTR6HTR1DHSD17B10KDM4EALDH1A1
SCHEMBL12720798 0.75 CYP1A2 (0.76) HTR6HTR1DHSD17B10CYP1A2CYP2C9
SCHEMBL1320834 0.74 HTR1D (0.67) HTR6HTR1DHSD17B10KDM4EALDH1A1
SCHEMBL27566660 0.74 NQO2 (0.72) HTR6HTR1DHSD17B10KDM4EALDH1A1
Hydrochloric Acid SCHEMBL16711692 0.74 HTR1D (0.60) HTR6HTR1DHSD17B10KDM4EALDH1A1
SCHEMBL5634953 0.74 HTR1D (0.58) HTR6HTR1DHSD17B10KDM4EALDH1A1
SCHEMBL3221458 0.72 KDM4E (0.84) HSD17B10KDM4EALDH1A1HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103050629-B A kind of manufacture method of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CENTER (CN) 2016-04-06 CN disclosed
CN-103044390-B Manufacturing method of active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2015-02-25 CN disclosed
CN-101906093-B Benzo five-membered unsaturated heterocycle compound and preparation method thereof INST MEDICINAL BIOTECHNOLOGY 2013-07-10 CN disclosed
CN-103044389-A Compound used as active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN disclosed
CN-103050628-A Method for producing ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN disclosed
CN-103044390-A Manufacturing method of active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN disclosed
CN-103050629-A Method for producing ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN disclosed
CN-101906093-A Benzo five-membered unsaturated heterocycle compound and preparation method thereof INST OF MEDICINAL BIOTECHNOLOGY OF CHINESE ACADEMY OF MEDICAL SCIENCES 2010-12-08 CN disclosed