Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.65 |
| ▸ | HTR6 | P50406 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | NQO2 | P16083 | 3/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28793909 | 0.88 | HTR6 (0.50) | HTR1DHTR6ALDH1A1KDM4EHPGD | |
| SCHEMBL16716149 | 0.86 | HTR1D (0.61) | HTR1DHTR6ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL16711692 | 0.85 | HTR1D (0.60) | HTR1DHTR6ALDH1A1KDM4EHPGD | |
| SCHEMBL27566660 | 0.85 | NQO2 (0.72) | HTR1DHTR6ALDH1A1KDM4EHPGD | |
| SCHEMBL6948872 | 0.84 | KDM4E (0.58) | HTR1DHTR6ALDH1A1KDM4EHPGD | |
| SCHEMBL3221458 | 0.84 | KDM4E (0.84) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL1345727 | 0.82 | KDM4E (0.73) | HTR1DHTR6ALDH1A1KDM4EHPGD | |
| SCHEMBL6950433 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| Hydrochloric Acid SCHEMBL1343869 | 0.81 | ALDH1A1 (0.72) | HTR1DHTR6ALDH1A1KDM4EHPGD | |
| SCHEMBL4244966 | 0.79 | HTR1D (1.00) | HTR1DHTR6ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011112167-A1 | COMPOSITIONS AND METHODS FOR DIABETES TREATMENT | RESET THERAPEUTICS, INC. (US) | 2011-09-15 | — | — | WO | disclosed |