Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | ASAH1 | Q13510 | 8/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29795738 | 1.00 | ALDH1A1 (0.65) | ALDH1A1TSHRASAH1GAAL3MBTL1 | |
| SCHEMBL28794854 | 0.86 | ASAH1 (0.69) | ALDH1A1TSHRASAH1GAAL3MBTL1 | |
| SCHEMBL28794631 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TSHRASAH1GAAHTT | |
| SCHEMBL29795450 | 0.86 | ASAH1 (0.69) | ALDH1A1TSHRASAH1GAAL3MBTL1 | |
| SCHEMBL9577554 | 0.86 | ASAH1 (0.63) | ALDH1A1TSHRASAH1GAAHTT | |
| SCHEMBL4399571 | 0.85 | ALDH1A1 (0.64) | ALDH1A1TSHRASAH1GAAHTT | |
| SCHEMBL7639089 | 0.82 | ASAH1 (0.73) | ALDH1A1TSHRASAH1GAAHTT | |
| SCHEMBL11743315 | 0.81 | ASAH1 (0.90) | ALDH1A1TSHRASAH1LMNASMN1; SMN2 | |
| SCHEMBL29795389 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TSHRASAH1GAAL3MBTL1 | |
| SCHEMBL28794567 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TSHRASAH1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787136-A | Substituted benzimidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |