SCHEMBL4399571

SCHEMBL4399571

CCCCNC(=O)n1c(OC(=O)NC)nc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.64
TSHR P16473 1/20 0.64
ASAH1 Q13510 8/20 0.58
GAA P10253 1/20 0.43
HTT P42858 1/20 0.43
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
CNR2 P34972 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577554 0.87 ASAH1 (0.63) ALDH1A1TSHRASAH1GAAHTT
SCHEMBL29795738 0.85 ALDH1A1 (0.65) ALDH1A1TSHRASAH1GAAHTT
SCHEMBL28794826 0.85 ALDH1A1 (0.65) ALDH1A1TSHRASAH1GAAHTT
SCHEMBL28794631 0.83 ALDH1A1 (0.62) ALDH1A1TSHRASAH1GAAHTT
SCHEMBL9239139 0.82 ALDH1A1 (0.62) ALDH1A1TSHRASAH1GAAHTT
SCHEMBL11884864 0.80 TSHR (0.74) ALDH1A1TSHRASAH1GAAHTT
SCHEMBL7639089 0.79 ASAH1 (0.73) ALDH1A1TSHRASAH1GAAHTT
SCHEMBL11743315 0.78 ASAH1 (0.90) ALDH1A1TSHRASAH1LMNASMN1; SMN2
Benomyl SCHEMBL29379464 0.78 TSHR (1.00) ALDH1A1TSHRASAH1GAAHTT
Benomyl SCHEMBL8379451 0.78 TSHR (1.00) ALDH1A1TSHRASAH1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0337103-B1 BIOCIDAL COMPOSITION ISHIHARA SANGYO KAISHA, Ltd. (JP) 1993-02-10 EP claimed
EP-0330979-A2 Aqueous composition for the treatment of textiles and method of making textile materials crease-proof Pfersee Chemie GmbH (DE) 1989-09-06 EP claimed
EP-0257828-A1 Dipropargyloxybenzene compounds and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-02 EP claimed
EP-0217579-A1 Fungicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-04-08 EP claimed
JP-57091906-A None JP disclosed
JP-2300104-A None JP disclosed
JP-59231005-A None JP disclosed
US-10448642-B2 Composition for preparing emulsion or microemulsion NIPPON SODA CO., LTD. (JP) 2019-10-22 US disclosed
US-20170112134-A1 COMPOSITION FOR PREPARING EMULSION OR MICROEMULSION NIPPON SODA CO., LTD. (JP) 2017-04-27 US disclosed
US-8729093-B2 Soil treating agent or seed treating agent comprising quinoline compounds or salts thereof as active ingredient, or method for preventing plant diseases by using the same MITSUI CHEMICALS AGRO, INC. (JP) 2014-05-20 US disclosed
EP-2103214-B1 USE OF QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENTS IN SOIL- OR SEED-TREATING AGENTS AND METHOD FOR CONTROL OF PLANT DISEASE MITSUI CHEMICALS AGRO INC (JP) 2013-10-23 EP disclosed
US-20090325998-A1 SOIL TREATING AGENT OR SEED TREATING AGENT COMPRISING QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENT,OR METHOD FOR PREVENTING PLANT DISEASES BY USING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2009-12-31 US disclosed
EP-0345775-B1 OXA- OR THIA-ZOLINE DERIVATIVE YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) 1992-04-08 EP disclosed
US-5087475-A PROCESS FOR THE FILM-COATING OF SEED MATERIALS ETABLISSEMENTS CERES (FR) 1992-02-11 US disclosed
EP-0467792-A1 Fungicidal composition for the treatment of seeds RHONE-POULENC AGROCHIMIE (FR) 1992-01-22 EP disclosed
JP-H02300104-A BACTERIOCIDAL COMPOSITION FOR AGRICULTURAL AND HORTICULTURAL USE SUMITOMO CHEM CO LTD 1990-12-12 JP disclosed
US-H811-H MIXTURE OF IMIDAZOLE COMPOUND AND OTHER PESTICIDE ISHIHARA SANGYO KAISHA LTD. (JP) 1990-08-07 US disclosed
EP-0337103-A2 Biocidal composition ISHIHARA SANGYO KAISHA, Ltd. (JP) 1989-10-18 EP disclosed
JP-S59231005-A AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION SUMITOMO CHEM CO LTD 1984-12-25 JP disclosed
JP-S5791906-A ANTIFUNGAL COMPOSITION FOR AGRICULTURAL AND HORTICULTURAL PURPOSE SUMITOMO CHEM CO LTD 1982-06-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090325998-A1 SOIL TREATING AGENT OR SEED TREATING AGENT COMPRISING QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENT,OR METHOD FOR PREVENTING PLANT DISEASES BY USING THE SAME RABL3, H1-3, RECQL ALDH1A1 999/4885TSHR 3065/4885ASAH1 1094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.