Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 11/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28813467 | 0.98 | ADAM17 (0.43) | ADAM17TP53ALDH1A1TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27853812 | 0.98 | ADAM17 (0.43) | ADAM17TP53ALDH1A1TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27853818 | 0.98 | ADAM17 (0.43) | ADAM17TP53ALDH1A1TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1504871 | 0.98 | ADAM17 (0.43) | ADAM17TP53ALDH1A1TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27977400 | 0.98 | ADAM17 (0.43) | ADAM17TP53ALDH1A1TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1504765 | 0.98 | ADAM17 (0.43) | ADAM17TP53ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL25723890 | 0.86 | ADAM17 (0.44) | ADAM17TP53ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL995413 | 0.82 | ALDH1A1 (0.39) | ADAM17TP53ALDH1A1TDP1KMT2A | |
| SCHEMBL995409 | 0.82 | ALDH1A1 (0.39) | ADAM17TP53ALDH1A1TDP1KMT2A | |
| SCHEMBL995410 | 0.82 | ALDH1A1 (0.39) | ADAM17TP53ALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471260-B | Novel benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-10-22 | — | — | CN | disclosed |
| CN-102471260-A | Novel benzenesulfonamide compounds, process for their synthesis and their use in pharmaceuticals and cosmetics | GALDERMA RES & DEV | 2012-05-23 | — | — | CN | disclosed |