Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802995 | 0.93 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2SIRT6KMT2A | |
| SCHEMBL28795481 | 0.89 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2SIRT6KMT2A | |
| Trifluoroacetic Acid SCHEMBL28795110 | 0.86 | FFAR4 (0.38) | ALDH1A1LMNASMN1; SMN2SIRT6KMT2A | |
| SCHEMBL28795201 | 0.84 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2SIRT6KMT2A | |
| SCHEMBL29803025 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2SIRT6KMT2A | |
| SCHEMBL22182766 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2SIRT6KMT2A | |
| SCHEMBL29785394 | 0.84 | SIRT6 (0.48) | ALDH1A1LMNASMN1; SMN2SIRT6KMT2A | |
| SCHEMBL22028007 | 0.84 | SIRT6 (0.48) | ALDH1A1LMNASMN1; SMN2SIRT6KMT2A | |
| SCHEMBL28795309 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2SIRT6KMT2A | |
| SCHEMBL29802998 | 0.83 | DRD2 (0.41) | ALDH1A1LMNASMN1; SMN2SIRT6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805303-A | Molecule with double functions of degrading EGFR (epidermal growth factor receptor), composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-07-29 | — | — | CN | disclosed |