Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12179763 | 0.85 | CHRNB2 (0.47) | CHRNB2CHRNA4 | |
| Ethoxycarbonyl Group SCHEMBL27657859 | 0.76 | RAB9A (0.41) | KDM4E | |
| SCHEMBL28934574 | 0.76 | CHRNB2 (0.44) | CHRNB2CHRNA4KDM4E | |
| SCHEMBL30108653 | 0.76 | CHRNB2 (0.44) | CHRNB2CHRNA4KDM4E | |
| SCHEMBL188568 | 0.75 | CHRNB2 (0.49) | CHRNB2CHRNA4CYP11B1CYP11B2 | |
| Ethoxycarbonyl Group SCHEMBL28203486 | 0.75 | KDM4E (0.39) | KDM4E | |
| Benzoic Acid SCHEMBL23501628 | 0.73 | ALOX15 (0.48) | — | |
| SCHEMBL13779692 | 0.72 | CHRNB2 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL30174297 | 0.71 | CHRNB2 (0.49) | CHRNB2CHRNA4 | |
| SCHEMBL428322 | 0.71 | CHRNB2 (0.49) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102365281-A | Indolizine derivative and medical application thereof | KISSEI PHARMACEUTICAL | 2012-02-29 | — | — | CN | disclosed |