Methyl Alcohol

Methyl Alcohol

SCHEMBL28795455

CO.COC(=O)C1Cc2ccccc2N1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.63
MAPT P10636 2/20 0.63
BACE1 P56817 1/20 0.43
KDM4E B2RXH2 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
CYP2C19 P33261 1/20 0.42
EPHX2 P34913 1/20 0.42
SMYD3 Q9H7B4 1/20 0.41
MTNR1A P48039 3/20 0.40
KMT2A Q03164 2/20 0.40
MTNR1B P49286 1/20 0.40
MEN1 O00255 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL644461 0.98 GAA (0.65) GAAMAPTBACE1KDM4EHSD17B10
SCHEMBL926891 0.98 GAA (0.65) GAAMAPTBACE1KDM4EHSD17B10
SCHEMBL29569853 0.98 GAA (0.65) GAAMAPTBACE1KDM4EHSD17B10
SCHEMBL3989086 0.98 GAA (0.65) GAAMAPTBACE1KDM4EHSD17B10
Hydrochloric Acid SCHEMBL30046451 0.97 GAA (0.63) GAAMAPTBACE1KDM4EHSD17B10
Hydrochloric Acid SCHEMBL6397031 0.97 GAA (0.63) GAAMAPTBACE1KDM4EHSD17B10
Hydrochloric Acid SCHEMBL7950878 0.97 GAA (0.63) GAAMAPTBACE1KDM4EHSD17B10
Hydrochloric Acid SCHEMBL926973 0.97 GAA (0.63) GAAMAPTBACE1KDM4EHSD17B10
SCHEMBL3256392 0.86 GAA (0.61) GAAMAPTKDM4EHSD17B10ALDH1A1
SCHEMBL7294748 0.83 GAA (0.61) GAAMAPTEPHX2SMYD3MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102365021-A Novel benzodiazepine derivatives IMMUNOGEN INC 2012-02-29 CN disclosed