Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989086 | 1.00 | GAA (0.65) | GAAMAPTBACE1KDM4EHSD17B10 | |
| SCHEMBL29569853 | 1.00 | GAA (0.65) | GAAMAPTBACE1KDM4EHSD17B10 | |
| SCHEMBL926891 | 1.00 | GAA (0.65) | GAAMAPTBACE1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL7950878 | 0.98 | GAA (0.63) | GAAMAPTBACE1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL30046451 | 0.98 | GAA (0.63) | GAAMAPTBACE1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL6397031 | 0.98 | GAA (0.63) | GAAMAPTBACE1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL926973 | 0.98 | GAA (0.63) | GAAMAPTBACE1KDM4EHSD17B10 | |
| Methyl Alcohol SCHEMBL28795455 | 0.98 | GAA (0.63) | GAAMAPTBACE1KDM4EHSD17B10 | |
| SCHEMBL3256392 | 0.87 | GAA (0.61) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7294748 | 0.84 | GAA (0.61) | GAAMAPTEPHX2SMYD3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409517-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2024-12-12 | — | — | US | claimed |
| CN-118102889-A | Organic compound | 奇华顿股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-1759118-B | Diazepinoindole derivatives as kinase inhibitors | PFIZER | 2010-12-08 | — | — | CN | claimed |
| EP-1687270-A4 | METHOD FOR PREPARING (S)-INDOLINE-2-CARBOXYLIC ACID AND (S)-INDOLINE-2-CARBOXYLIC ACID METHYL ESTER USING HYDROLYTIC ENZYME | SK HOLDINGS CO LTD (KR) | 2009-05-20 | — | — | EP | claimed |
| CN-100463903-C | Method for preparing (s)-indoline-2-carboxylic acid and (s)-indoline-2-carboxylic acid methyl ester using hydrolytic enzyme | SK CORP (KR) | 2009-02-25 | — | — | CN | claimed |
| US-7405070-B2 | Method for preparing (s)-indoline-2-carboxylic acid and (s)-indoline-2-carboxylic acid methyl ester using hydrolytic enzyme | SK CORPORATION (KR) | 2008-07-29 | — | — | US | claimed |
| JP-2007512016-A | — | — | 2007-05-17 | — | — | JP | claimed |
| US-20070077632-A1 | Method for preparing (s)-indoline-2-carboxylic acid and (s)-indoline-2-carboxylic acid methyl ester using hydrolytic enzyme | SK CORPORATION (KR) | 2007-04-05 | — | — | US | claimed |
| CN-1886373-A | Method for preparing (s)-indoline-2-carboxylic acid and (s)-indoline-2-carboxylic acid methyl ester using hydrolytic enzyme | SK CORP (KR) | 2006-12-27 | — | — | CN | claimed |
| EP-1687270-A1 | METHOD FOR PREPARING (S)-INDOLINE-2-CARBOXYLIC ACID AND (S)-INDOLINE-2-CARBOXYLIC ACID METHYL ESTER USING HYDROLYTIC ENZYME | SK Corporation (KR) | 2006-08-09 | — | — | EP | claimed |
| CN-1759118-A | Diazepinoindole derivatives as kinase inhibitors | PFIZER (US) | 2006-04-12 | — | — | CN | claimed |
| WO-2005051910-A1 | METHOD FOR PREPARING (S)-INDOLINE-2-CARBOXYLIC ACID AND (S)-INDOLINE-2-CARBOXYLIC ACID METHYL ESTER USING HYDROLYTIC ENZYME | SK CORPORATION (KR) | 2005-06-09 | — | — | WO | claimed |
| JP-7258250-A | — | — | None | — | — | JP | disclosed |
| US-20240409517-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2024-12-12 | — | — | US | disclosed |
| US-20240409517-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2024-12-12 | — | — | US | disclosed |
| EP-4415561-A2 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2024-08-21 | — | — | EP | disclosed |
| WO-1995001353-A1 | ANTIHYPERTENSIVE TRICYCLIC AZEPINE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | CIBA-GEIGY AG (CH) | 1995-01-12 | — | — | WO | disclosed |
| WO-1993008188-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-04-29 | — | — | WO | disclosed |
| US-4599357-A | 1-mercaptoalkanoylindoline-2-carboxylic acids | CIBA-GEIGY CORPORATION (US) | 1986-07-08 | — | — | US | disclosed |
| US-3980797-A | Hexahydro-diazepino-indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409517-A1 | ORGANIC COMPOUNDS | HTR3C, HTR3A, H1-0 | GAA 3857/4885MAPT 1418/4885BACE1 3862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.