Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989086 | 1.00 | GAA (0.65) | GAAMAPTBACE1KDM4EHSD17B10 | |
| SCHEMBL644461 | 1.00 | GAA (0.65) | GAAMAPTBACE1KDM4EHSD17B10 | |
| SCHEMBL926891 | 1.00 | GAA (0.65) | GAAMAPTBACE1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL7950878 | 0.98 | GAA (0.63) | GAAMAPTBACE1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL30046451 | 0.98 | GAA (0.63) | GAAMAPTBACE1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL6397031 | 0.98 | GAA (0.63) | GAAMAPTBACE1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL926973 | 0.98 | GAA (0.63) | GAAMAPTBACE1KDM4EHSD17B10 | |
| Methyl Alcohol SCHEMBL28795455 | 0.98 | GAA (0.63) | GAAMAPTBACE1KDM4EHSD17B10 | |
| SCHEMBL3256392 | 0.87 | GAA (0.61) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7294748 | 0.84 | GAA (0.61) | GAAMAPTEPHX2SMYD3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2025-07-29 | — | — | US | disclosed |
| EP-3303367-B1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119613279-A | N-substituted benzene ring bioisostere and preparation method thereof | 上海交通大学 | 2025-03-14 | — | — | CN | disclosed |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | UNIV NEW YORK (US) | 2024-06-13 | — | — | US | disclosed |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2024-02-06 | — | — | US | disclosed |
| CN-116675704-A | Pyrrole derivative and preparation method and application thereof | 深圳市祥根生物医药有限公司 | 2023-09-01 | — | — | CN | disclosed |
| EP-4225303-A1 | STAT DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-116490069-A | STAT degradation agent and application thereof | 凯麦拉医疗公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-114644634-B | Pyrrole derivative and preparation method and application thereof | 深圳市祥根生物医药有限公司 | 2023-06-20 | — | — | CN | disclosed |
| US-20220289802-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | CORNELL UNIVERSITY | 2022-09-15 | — | — | US | disclosed |
| US-11440938-B2 | Stabilized minimal coiled-coil mimetics | NEW YORK UNIVERSITY (US) | 2022-09-13 | — | — | US | disclosed |
| CN-114644634-A | Pyrrole derivative and preparation method and application thereof | 深圳市祥根生物医药有限公司 | 2022-06-21 | — | — | CN | disclosed |
| WO-2022077010-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTIC, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | GAA 1295/4885MAPT 589/4885BACE1 2503/4885 |
| US-11440938-B2 | Stabilized minimal coiled-coil mimetics | COIL, CALCOCO2, SMC2 | GAA 1303/4885MAPT 20/4885BACE1 1202/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | GAA 2723/4885MAPT 4078/4885BACE1 2879/4885 |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | GAA 1295/4885MAPT 589/4885BACE1 2503/4885 |
| US-20220289802-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | GAA 1295/4885MAPT 589/4885BACE1 2503/4885 |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | GAA 1452/4885MAPT 548/4885BACE1 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.