Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22719982 | 0.92 | GPR84 (0.43) | CA2GPR84LMNAFAAH | |
| SCHEMBL27912254 | 0.82 | MGAM (0.41) | CA2CA1CYP3A4TSHRATM | |
| SCHEMBL27790069 | 0.79 | FAAH (0.37) | CA2CA1CYP3A4TSHRATM | |
| SCHEMBL2313022 | 0.78 | CYP3A4 (0.51) | CA2CA1CYP3A4TSHRATM | |
| SCHEMBL23723112 | 0.77 | ZDHHC7 (0.49) | CA2RECQLGPR84LMNAFAAH | |
| SCHEMBL28630516 | 0.77 | ZDHHC7 (0.41) | CA1GPR84FAAH | |
| SCHEMBL7493361 | 0.77 | CA2 (0.40) | CA2CA1MAPK1GPR84FDPS | |
| SCHEMBL6461000 | 0.77 | GPR84 (0.50) | CA2TSHRTDP1MAPK1GPR84 | |
| SCHEMBL6465070 | 0.77 | GPR84 (0.50) | CA2TSHRTDP1MAPK1GPR84 | |
| SCHEMBL8609138 | 0.77 | GPR84 (0.50) | CA2TSHRTDP1MAPK1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102276548-B | Method for synthesizing 2-iminothiazolidine-4-one and derivatives thereof | UNIV XI AN JIAOTONG | 2013-07-31 | — | — | CN | disclosed |
| CN-102276548-A | Method for synthesizing 2-iminothiazolidine-4-one and derivatives thereof | — | 2011-12-14 | — | — | CN | disclosed |