Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | ATP4A | P20648 | 2/20 | 0.41 |
| ▸ | ATP4B | P51164 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483872 | 0.79 | L3MBTL1 (0.55) | L3MBTL1PTGDR2ALOX5TRPM8KDM4E | |
| SCHEMBL12030444 | 0.78 | L3MBTL1 (0.54) | L3MBTL1PTGDR2ALOX5TRPM8KDM4E | |
| SCHEMBL2485046 | 0.77 | L3MBTL1 (0.53) | L3MBTL1PTGDR2ALOX5TRPM8KDM4E | |
| SCHEMBL2483841 | 0.74 | L3MBTL1 (0.59) | L3MBTL1ALOX5TRPM8KDM4E | |
| SCHEMBL2097759 | 0.65 | FFAR1 (0.53) | L3MBTL1TRPM8 | |
| SCHEMBL5750845 | 0.65 | HRH4 (0.49) | HRH3KDM4E | |
| SCHEMBL11994177 | 0.64 | ATP4A (0.58) | PTGDR2ATP4AATP4BKDM4EPOLB | |
| SCHEMBL2076554 | 0.64 | TRPM8 (0.64) | L3MBTL1PTGDR2TRPM8KDM4E | |
| SCHEMBL12049566 | 0.64 | L3MBTL1 (0.60) | L3MBTL1PTGDR2ALOX5TRPM8KDM4E | |
| SCHEMBL90811 | 0.64 | IDO1 (0.61) | L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102388054-A | Thiazolopyridine sirtuin modulating compounds | SIRTRIS PHARMACEUTICALS INC | 2012-03-21 | — | — | CN | disclosed |