Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 5/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719274 | 1.00 | FFAR1 (0.38) | FFAR1GABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL1662638 | 0.82 | L3MBTL1 (0.36) | LMNATSHRKMT2AMAPTALDH1A1 | |
| SCHEMBL16626887 | 0.79 | FFAR1 (0.37) | FFAR1GABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL25265377 | 0.79 | FFAR1 (0.37) | FFAR1GABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL2058832 | 0.70 | SELE (0.34) | LMNAALDH1A1 | |
| SCHEMBL310462 | 0.70 | RECQL (0.39) | LMNAALDH1A1 | |
| SCHEMBL11830388 | 0.69 | GABBR2 (0.37) | FFAR1GABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL22193617 | 0.68 | GABBR2 (0.69) | FFAR1GABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL11321913 | 0.68 | GABBR2 (0.69) | FFAR1GABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL7676112 | 0.68 | FFAR1 (0.37) | FFAR1GABBR2GABBR1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574852-B | AKT inhibitors | LILLY CO ELI | 2014-06-25 | — | — | CN | disclosed |
| CN-102574852-A | AKT inhibitors | LILLY CO ELI | 2012-07-11 | — | — | CN | disclosed |